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Table 2 Frequency of the TF and TFPI polymorphisms in CHD patients and healthy controls

From: Gender differences of polymorphisms in the TF and TFPI genes, as related to phenotypes in patients with coronary heart disease and type-2 diabetes

Genotype CHD n (%) Controls n (%) p
TF -1812   996   204  
CC 327 (32.8) 63 (30.9)  
CT 466 (46.8) 102 (50.0) >0.2
TT 203 (20.4) 39 (19.1)  
Allele T frequency 0.438   0.441   
TF -603   996   204  
AA 326 (32.7) 63 (30.9)  
AG 466 (46.8) 102 (50.0) > 0.2
GG 204 (20.5) 39 (19.1)  
Allele G frequency 0.439   0.441   
TF 5466   996   204  
AA 879 (88.3) 181 (88.7)  
AG 112 (11.3) 22 ) (10.8 > 0.2
GG 5 (0,5) 1 (0.5)  
Allele G frequency 0.061   0.059   
TFPI-399   996   204  
CC 758 (76.1) 158 (77.5)  
CT 224 (22.5) 41 (20.1) > 0.2
TT 14 (1.4) 5 (2.5)  
Allele T frequency 0.127   0.125   
TFPI -287 996    204  
TT 723 (72.6) 148 (72.6)  
TC 245 (24.6) 55 (27.0) > 0.2
CC 28 (2.8) 1 (0.5)  
Allele C frequency 0.151   0.140   
TFPI -33   996   203*  
TT 512 (51.4) 102 (50.3)  
TC 405 (40.7) 87 (42.9) > 0.2
CC 79 (7.9) 14 (6.9)  
Allele C frequency 0.283   0.283   
Haplotypes      
TF I 65 (6.5) 13 (6.4) > 0.2
  1. Calculations are performed with comparison of the heterozygous and homozygous pooled,
  2. versus the wild type.
  3. Haplotypes: TFI is the combination of TF -1812 CC and TF 5466 AG/GG
  4. p-values refer to differences between CHD patients and controls.
  5. *The TFPI -33 polymorphism was detectable in 203 out of 204 controls.