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Figure 5 | Thrombosis Journal

Figure 5

From: Impact of a high-fat meal on assessment of clopidogrel-induced platelet inhibition in healthy subjects

Figure 5

Correlation between fasting on-clopidogrel platelet reactivity and the change in on-treatment platelet reactivity after a high-fat meal for the VerifyNow P2Y12 assay. Spearman correlation coefficients (ρ) were generated for each assay to assess the correlation between: 1) fasting on-clopidogrel platelet reactivity and 2) the change in platelet reactivity on-clopidogrel from the fasting to the non-fasting state. The significant finding for the VerifyNow P2Y12 assay (p = 0.008) suggests that subjects with high platelet reactivity on clopidogrel may be selectively impacted by the high-fat meal, while subjects with a normal clopidogrel response may have more consistent results regardless whether or not a high-fat meal is taken.

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