Figure 2From: A randomized, open-label trial of edoxaban in Japanese patients with severe renal impairment undergoing lower-limb orthopedic surgery Patient disposition. CLCR = creatinine clearance; EDX = edoxaban; FPX = fondaparinux; MiRI = mild renal impairment; SRI = severe renal impairment. aOne patient randomized to FPX 1.5 mg discontinued prior to initiation of study treatment due to excessive bleeding from the surgical wound.Back to article page