Assay
|
Sample type
|
Adhesion
|
Aggregation
|
Coagulation
|
Endothelium
|
Shear
|
No. of citations
|
|---|
| | Plasma | PRP | WB | | | Init. | Prop. | Elast. | Lysis | | | |
Multiplate |
-
|
+
|
+
|
-
|
+
|
-
|
-
|
-
|
-
|
-
|
-
| 250 |
VerifyNow |
-
|
-
|
+
|
-
|
+
|
-
|
-
|
-
|
-
|
-
|
-
| 476 |
Plateletworks |
-
|
-
|
+
|
-
|
+
|
-
|
-
|
-
|
-
| - |
-
| 26 |
Impact-R |
-
|
-
|
+
|
+
|
+
|
-
|
-
|
-
|
-
|
-
|
+
| 121 |
PFA-100 |
-
|
-
|
+
|
+
|
+
|
-
|
-
|
-
|
-
|
-
|
+
| 745 |
Perfusion chambers |
-
|
-
|
+
|
+
|
+
| (+) | (+) |
-
|
-
| (+) |
+
| 630 |
TEG | (+) |
+
|
+
|
-
|
-
|
-
|
+
|
+
|
+
|
-
|
-
| 4016 |
ROTEM | (+) |
+
|
+
|
-
|
-
|
-
|
+
|
+
|
+
|
-
|
-
| 3932 |
ReoRox | (+) |
+
|
+
|
-
|
-
|
+
|
+
|
+
|
+
|
-
|
-
| 28 |
Sonoclot | (+) |
+
|
+
|
-
|
-
|
+
|
+
|
+
|
+
|
-
|
-
| 113 |
Thrombin generation |
+
|
+
|
−
|
-
|
-
|
+
|
+
|
−
|
−
|
-
|
-
| 118 |
OHP |
+
|
−
|
−
|
-
|
-
| + | (+) |
-
|
+
|
-
|
-
| 23 |
Thrombodynamics |
+
|
+
|
+
|
-
|
-
|
+
|
+
|
−
|
−
|
-
|
-
| 11 |
- The assays ability to measure adhesion, aggregation, coagulation in terms of initiation (Init.), propagation (Prop.), clot elasticity (Elast) and fibrinolysis (Lysis). The table shows the type of sample (plasma, platelet-rich-plasma (PRP) or whole blood (WB)) that can be assessed in each assay. The table also shows if the measurement can include the contribution by endothelium and shear components. Plus (+) means yes and minus (−) means no, signs within parentheses means possible in theory, but not commonly used. For the propagation component, the perfusion chambers and the Thrombodynamics detects spatial clot propagation, whereas the other techniques detects other processes occurring after the initial clotting and first fibrin fibres have formed as propagation. To reflect how common these different assays are, we present the number of citations found on PubMed on the 30th of November 2014.
