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Table 1 Aspects of global haemostasis assays

From: Assays of different aspects of haemostasis – what do they measure?

Assay Sample type Adhesion Aggregation Coagulation Endothelium Shear No. of citations
  Plasma PRP WB    Init. Prop. Elast. Lysis    
Multiplate - + + - + - - - - - - 250
VerifyNow - - + - + - - - - - - 476
Plateletworks - - + - + - - - - - - 26
Impact-R - - + + + - - - - - + 121
PFA-100 - - + + + - - - - - + 745
Perfusion chambers - - + + + (+) (+) - - (+) + 630
TEG (+) + + - - - + + + - - 4016
ROTEM (+) + + - - - + + + - - 3932
ReoRox (+) + + - - + + + + - - 28
Sonoclot (+) + + - - + + + + - - 113
Thrombin generation + + - - + + - - 118
OHP + - - + (+) - + - - 23
Thrombodynamics + + + - - + + - - 11
  1. The assays ability to measure adhesion, aggregation, coagulation in terms of initiation (Init.), propagation (Prop.), clot elasticity (Elast) and fibrinolysis (Lysis). The table shows the type of sample (plasma, platelet-rich-plasma (PRP) or whole blood (WB)) that can be assessed in each assay. The table also shows if the measurement can include the contribution by endothelium and shear components. Plus (+) means yes and minus (−) means no, signs within parentheses means possible in theory, but not commonly used. For the propagation component, the perfusion chambers and the Thrombodynamics detects spatial clot propagation, whereas the other techniques detects other processes occurring after the initial clotting and first fibrin fibres have formed as propagation. To reflect how common these different assays are, we present the number of citations found on PubMed on the 30th of November 2014.