Table 2 List of case reports and case series about thrombotic manifestations in FMF patients
From: Autoinflammatory diseases: a possible cause of thrombosis?
Authors | Type of publication | Thrombotic manifestation | Other thrombosis risk factors | Genetically proven FMF |
|---|---|---|---|---|
Joo K et al. | Case report | total thrombosis of splenic vein with partial thrombosis of proximal superior mesenteric vein, main portal vein and intrahepatic both portal vein | Decreased protein S activity | 3 mutations (p.Glu148Gln,p.Pro369Ser, p.Arg408Gln) |
Ambartsymian SV | Autoptic case series (68 patients) | amyloid angiopathias, with narrowing or obstructing of arterioles and coronary vasculitis | Data not available | Data not available |
Luger S et al. | Case report | Brain stem infarction due to CNS vasculitis | Data not available | Yes |
Feld O et al. | Review and case-series (11 patients) | Stroke/TIA | renal amyloidosis and haemodialysis, and three had smoking, hypertension, diabetes mellitus and obesity | Data not available |
Unal F et al. | Case series (2 patients) | Budd-Chiari syndrome | Data not available | Yes |
Korkmaz C et al. | Review and case series (2 patients) | 1. Left cerebral infarct 2. Suspected mesenteric ischemia | Amyloidosis, anticardiolipin antibodies Pregnancy | Yes Homozigosity for M694V Data not available |
Ruiz XD et al. | Case report | Pulmonary embolism | Data not available | Heterozygous M649V |
Standing AS et al. | Case report | Budd-Chiari syndrome | Heterozygous for MTHFR mutation | Homozygous E148Q |
Kalyonku U et al. | Case series (7 patients) | Cerebrovascular accident | In 3 patients: significant patent foramen ovale, thalassaemia major and carotid artery dissection | Yes All homozygosis for MEFV mutations (6/7 homozygosis for M694V) |
Sari S et al. | Case series (2 patients) | Budd-Chiari syndrome | FV Leiden single mutation Homozygosity for MTHFR mutation | Yes Homozygosity for M694V |
Aoun G et al. | Case report | Stroke (right lateral medullary syndrome) | Lupus anticoagulant FV leiden and MTHFR heterozygous mutations | Yes Homozygosity for M694V |
Uyarel U et al. | Case report | Acute myocardial infarction | No known coronary risk factors | Data not available |
Serrano R et al. | Case report | Acute myocardial infarction due to coronary vasculitis | Amyloidosis Chronic renal failure on hemodyalisis Cyclosporin | Data not available |
Ustundag Y et al. | Case report | Superior vena cava thrombosis | Obesity | Not available |
Finsterer J et al. | Case report | CNS and PNS vasculitis or amyloidosis | Data not available | Yes Homozygosity for M694V |
Reuben A et al. | Case series (7 patients) | Renal vein thrombosis | Amyloidosis | Data not available |
Puricel S et al. | Case series (1 patient) | Acute coronary syndrome | Data not available | Data not available |
Lidar M et al. | Case series (6 patients) | Thrombo-embolism | Data not available | Data not available |