Table 2 Incidence of clinical events in EINSTEIN DVT [25] and EINSTEIN PE [26]
Probability, mean (SE) | EINSTEIN DVT | EINSTEIN PE |
|---|---|---|
Recurrent VTE (LMWH/VKA) | ||
3-month population | ||
0–3 months | 0.015 (0.008) | 0.016 (0.011) |
6-month population | ||
0–3 months | 0.024 (0.005) | 0.016 (0.003) |
3–6 months | 0.003 (0.002) | 0.002 (0.001) |
12-month population | ||
0–3 months | 0.035 (0.009) | 0.015 (0.004) |
3–6 months | 0.008 (0.004) | 0.003 (0.002) |
6–12 months | 0.003 (0.003) | 0.001 (0.001) |
Lifelong population [61] | ||
>12Â months | 0.700 (0.107) | 0.700 (0.107) |
Major bleeding (LMWH/VKA) | ||
3-month population | ||
0–3 months | 0.020 (0.010) | 0.041 (0.018) |
6-month population | ||
0–3 months | 0.009 (0.003) | 0.010 (0.003) |
3–6 months | 0.004 (0.002) | 0.008 (0.003) |
12-month population | ||
0–3 months | 0.002 (0.002) | 0.013 (0.004) |
3–6 months | – (0.002) | 0.004 (0.002) |
6–12 months | – (0.002) | 0.006 (0.003) |
Lifelong population [61] | ||
>12Â months | 1.600 (0.245) | 1.600 (0.245) |
NMCR bleeding (LMWH/VKA) | ||
3-month population | ||
0–3 months | 0.060 (0.017) | 0.066 (0.022) |
6-month population | ||
0–3 months | 0.047 (0.006) | 0.067 (0.007) |
3–6 months | 0.013 (0.004) | 0.022 (0.004) |
12-month population | ||
0–3 months | 0.049 (0.01) | 0.062 (0.008) |
3–6 months | 0.024 (0.008) | 0.029 (0.006) |
6–12 months | 0.038 (0.01) | 0.030 (0.006) |
Lifelong population | ||
>12Â months | 0.014 (0.002) | 0.022 (0.002) |