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Table 3 Stroke risk scoring systems: CHADS2 and CHA2DS2-VASc

From: A case-based approach to implementing guidelines for stroke prevention in patients with atrial fibrillation: balancing the risks and benefits

CHADS2 score

Scoring system

Stroke rates associated with CHADS2 score

 

Risk factor

Points

Risk score

Adjusted stroke rate (%/y)a, b (95 % CI)

Risk of stroke

C

CHF

1

0

1.9 (1.2, 3.0)

Low

H

Hypertension

1

1

2.8 (2.0, 3.8)

Moderate

A

Age ≥75 y

1

2

4.0 (3.1, 5.1)

D

Diabetes

1

3

5.9 (4.6, 7.3)

S2

Prior stroke/TIA

2

4

8.5 (6.3, 11.1)

High

5

12.5 (8.2, 17.5)

6

18.2 (10.5, 27.4)

CHA2DS2-VASc score

Scoring system

Stroke rates associated with CHA2DSs-VASc score

 

Risk factor

Points

Risk score

TE rate during 1 year (% [95 % CI])c, d

Risk of stroke

C

CHF/LV dysfunction

1

0

0

Low

H

Hypertension

1

1

0.6 (0.0, 3.4)

Moderate

A2

Age ≥75 y

2

2

1.6 (0.3, 4.7)

D

Diabetes

1

3

3.9 (1.7, 7.6)

High

S2

Prior stroke/TIA/TE

2

4

1.9 (0.5, 4.9)

V

Vascular disease (prior MI, PAD, or aortic plaque)

1

5

3.2 (0.7, 9.0)

A

Age 65–74 y

1

6

3.6 (0.4, 12.3)

Sc

Sex category (female sex)

1

7

8.0 (1.0, 26.0)

  1. CHF congestive heart failure, CI confidence interval, LV left ventricular, MI myocardial infarction, PAD peripheral artery disease, TE thromboembolism, TIA transient ischemic attack
  2. aAdapted from Gage BF et al. JAMA. 2001;285:2864–70 [33]
  3. bAdjusted stroke is expected stroke rate per 100 person-years from exponential survival model, assuming no aspirin was taken
  4. cAdapted from Lip GYH et al. Chest. 2010;137:263–72 [34]
  5. dp value for trend = 0.003
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Thrombosis Journal

ISSN: 1477-9560

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