Characteristic | Edoxaban 30 mg QD (n = 255) | Enoxaparin 2000 IU BID (n = 248) |
---|---|---|
Sex | ||
Female | 220 (86.3) | 212 (85.5) |
Age (y) | ||
Mean ± SD | 62.8 ± 9.61 | 62.8 ± 9.72 |
<75 | 220 (86.3) | 217 (87.5) |
≥75 | 35 (13.7) | 31 (12.5) |
Weight (kg) | ||
Mean ± SD | 57.7 ± 9.72 | 57.0 ± 9.60 |
<60 | 160 (62.7) | 157 (63.3) |
≥60 | 95 (37.3) | 91 (36.7) |
BMI, mean ± SD | 24.5 ± 3.52 | 24.2 ± 3.60 |
CL CR (mL/min) | ||
Mean ± SD | 89.6 ± 29.58 | 88.9 ± 26.49 |
≥80 | 148 (58.0) | 150 (6) |
≥50 to <80 | 93 (36.5) | 91 (36.7) |
<50 | 14 (5.5) | 7 (2.8) |
History of artificial joint replacement of the lower limbs | 39 (15.3) | 35 (14.1) |
Duration from the end of surgery to the start of study treatment (h) | ||
≥12 to <18 | 16 (6.3) | - |
≥18 to ≤24 | 239 (93.7) | - |
≥24 to <30 | - | 170 (68.5) |
≥30 to <36 | - | 78 (31.5) |
Hour:minute, Mean ± SD | 21:40 (1:54) | 28:37 (3:00) |
Physiotherapy a | ||
Intermittent pneumatic compression therapy (foot sole) | 137 (53.7) | 135 (54.4) |
Intermittent pneumatic compression therapy (lower legs and thigh) | 120 (47.1) | 114 (46.0) |
Elastic stockings | 209 (82.0) | 201 (81.0) |
Concomitant NSAIDs | 250 (98.0) | 243 (98.0) |
Treatment duration (days) | ||
Mean ± SD | 12.5 (1.4) | 12.5 (1.5) |