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Table 12 Major complications related to study drugs

From: Low dose compared to variable dose Warfarin and to Fondaparinux as prophylaxis for thromboembolism after elective hip or knee replacement surgery; a randomized, prospective study

Relationship to study drug n Description Study arm
Possibly related 1 Painless hematochezia following hard bowel movement (minor) B
Probably related 1 Hematoma, operative leg, from post-op trauma (minor; delayed discharge) B
1 Hematoma evaluated, no intervention required (minor; delayed discharge) B
Related 1 Hemorrhage with ischemic colitis. INR prolonged on 1 mg warfarin C
   per day due to VKORC-1 genome disorder. (major; readmitted to hospital)