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Table 2 Exclusion criteria

From: Low dose compared to variable dose Warfarin and to Fondaparinux as prophylaxis for thromboembolism after elective hip or knee replacement surgery; a randomized, prospective study

1. Abnormal platelet count, prothrombin time (PT) or partial thromboplastin time (PTT)
2. Surgery for acute fracture (<4 weeks), septic joint, or extraction arthroplasty
3. History of VTE or documented hypercoagulation syndrome
4. Increased risk of hemorrhage, as from active gastric ulcer or urinary tract bleed within the last year
5. Hemorrhagic stroke; brain, spinal, or ophthalmologic surgery in previous 6 months
6. Liver enzymes or bilirubin greater than 2 x normal
7. Decreased renal function with GFR <30 ml/min.
8. Cancer in last year, other than localized cancers of the skin
9. Requires chronic anticoagulation
10. Requires chronic platelet function suppressive therapy
11. Prior adverse reaction to any of the study drugs
12. Uncontrolled hypertension
13. BMI >42
14. Pregnancy