Fig. 3
From: Validation of a modified thromboelastometry approach to detect changes in fibrinolytic activity
Boxplots of different ROTEM parameters at 125 ng/mL rTPA in healthy volunteers and patient groups. Sepsis and CTS are significantly different to HV (p < 0.001) for all four parameters. The grey area depicts the 95 % reference ranges as was calculated using the healthy volunteer data from Table 1. CTS-TXA cardiothoracic surgery patients using tranexamic acid, HV healthy volunteers, rTPA recombinant tissue plasminogen activator, CT clotting time, MCF maximum clot firmness, LOT lysis onset time, LT lysis time, FS fibrinolysis speed, defined as the decline in %/min between the LOT and LT points thus: FS = 75/(LTmin-LOTmin); FSc, corrected fibrinolysis speed in mm/min between the LOT and LT points thus: FSc = (amplitudeLOT-amplitudeLT)/(LTmin-LOTmin)