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Fig. 4 | Thrombosis Journal

Fig. 4

From: Validation of a modified thromboelastometry approach to detect changes in fibrinolytic activity

Fig. 4

Boxplots of different ROTEM parameters at 175 ng/mL rTPA in healthy volunteers and patient groups. Sepsis and CTS are significantly different to HV (p < 0.001) for all four parameters. The grey area depicts the 95 % reference ranges as was calculated using the healthy volunteer data from Table 1. CTS-TXA; cardiothoracic surgery patients using tranexamic acid; HV, healthy volunteers; rTPA, recombinant tissue plasminogen activator; CT, clotting time; MCF, maximum clot firmness; LOT, lysis onset time; LT, lysis time; FS, fibrinolysis speed, defined as the decline in %/min between the LOT and LT points; thus: FS = 75/(LTmin-LOTmin); FSc, corrected fibrinolysis speed in mm/min between the LOT and LT points; thus: FSc = (amplitudeLOT-amplitudeLT)/(LTmin-LOTmin)

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