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Table 3 Prognostic test characteristics for 30 day mortality

From: External validation of prognostic rules for early post-pulmonary embolism mortality: assessment of a claims-based and three clinical-based approaches

 

IMPACT

PESI

sPESI

Hestia

Low-Risk Mortality

1/165

3/218

1/177

0/160

n/N (%)

(0.6 %)

(1.4 %)

(0.6 %)

(0 %)

High-Risk Mortality

32/408

30/355

32/396

33/413

n/N (%)

(7.8 %)

(8.5 %)

(8.1 %)

(8.0 %)

Sensitivity

97.0 %

90.9 %

97.0 %

100 %

(95 % CI)

(82.5–99.8 %)

(74.5–97.6 %)

(82.5–99.8 %)

(87.0–100 %)

Specificity

30.4 %

39.8 %

32.6 %

29.6 %

(95%CI)

(26.6–34.5 %)

(35.7–44.1 %)

(28.7–36.8 %)

(25.8–33.7 %)

PPV

7.8 %

8.5 %

8.1 %

8.0 %

(95 % CI)

(5.5–11.0 %)

(5.9–12.0 %)

(5.7–11.3 %)

(5.6–11.1 %)

NPV

99.4 %

98.6 %

99.4 %

100 %

(95 % CI)

(96.2–100 %)

(95.7–99.6 %)

(96.4–100 %)

(97.1–100 %)

C-statistic

0.804

0.805

0.731

0.791

(95 % CI)

(0.749–0.859)

(0.731–0.879)

(0.653–0.810)

(0.721–0.860)

  1. CI confidence interval, IMPACT In-hospital Mortality for Pulmonary embolism using Claims data, NPV negative predictive value, PESI Pulmonary Embolism Severity Index, PPV positive predictive value, sPESI simplified Pulmonary Embolism Severity Index