Table 1 Baseline patient characteristics – treated set
THR | TKR | P valuea | Total | |
|---|---|---|---|---|
Treated, n | 2734 | 2558 | 5292 | |
Male, n (%) | 1293 (47.3) | 938 (36.7) | <0.0001 | 2231 (42.2) |
Age (years), mean (SD) | 60.8 (10.22) | 64.6 (7.50) | <0.0001 | 62.6 (9.20) |
Age by category | <0.0001 | |||
<65 years, n (%) | 1586 (58.0) | 1117 (43.7) | 2703 (51.1) | |
≥65 years, n (%) | 1148 (42.0) | 1441 (56.3) | 2589 (48.9) | |
BMI (kg/m2), mean (SD) | 27.8 (4.74) | 30.5 (5.25) | <0.0001 | 29.1 (5.16) |
CrCl [mL/min] at visit 1, mean (SD) | 109.9 (115.73) | 106.1 (70.71) | 0.1425 | 108.1 (96.57) |
Medical history | ||||
Any, n (%) | 1357 (49.6) | 1639 (64.1) | <0.0001 | 2996 (56.6) |
Hypertension, n (%) | 1153 (42.2) | 1448 (56.6) | <0.0001 | 2601 (49.1) |
Diabetes mellitus, n (%) | 207 (7.6) | 324 (12.7) | <0.0001 | 531 (10.0) |
Cancer, n (%) | 179 (6.5) | 197 (7.7) | 0.1024 | 376 (7.1) |
Liver disease, n (%) | 59 (2.2) | 64 (2.5) | 0.4066 | 123 (2.3) |
Renal disease, n (%) | 44 (1.6) | 73 (2.9) | 0.0021 | 117 (2.2) |
TIA/stroke, n (%) | 44 (1.6) | 54 (2.1) | 0.1761 | 98 (1.9) |
MI, n (%) | 33 (1.2) | 58 (2.3) | 0.0030 | 91 (1.7) |
GI bleeding, n (%) | 23 (0.8) | 42 (1.6) | 0.0082 | 65 (1.2) |
Immobilisation within the last 10 days | 6 (0.2) | 5 (0.2) | 0.8481 | 11 (0.2) |
Risk factor subgroups | ||||
Active smoker, n (%) | 465 (17.0) | 239 (9.3) | <0.0001 | 704 (13.3) |
CAD, n (%) | 132 (4.8) | 187 (7.3) | 0.0001 | 319 (6.0) |
CHF, n (%) | 54 (2.0) | 73 (2.9) | 0.0369 | 127 (2.4) |
History of VTE, n (%) | 73 (2.7) | 113 (4.4) | 0.0006 | 186 (3.5) |
Concomitant ASA, n (%) | 166 (6.1) | 252 (9.9) | <0.0001 | 418 (7.9) |
Chronic use of NSAIDs, n (%) | 415 (15.2) | 394 (15.4) | 0.8214 | 809 (15.3) |