Clinical benefit of graduated compression stockings for prevention of venous thromboembolism after total knee arthroplasty: post hoc analysis of a phase 3 clinical study of edoxaban

Table 3 Incidence of VTE^a in patients using GCS for prophylaxis

	Edoxaban	Enoxaparin	Total
	N = 105	N = 96	N = 201
No mechanical prophylaxis	5.8 % (3/52)	20.8 % (10/48)	13.0 % (13/100)
Mechanical prophylaxis with GCS alone	3.8 % (2/53)	8.4 % (4/48)	6.0 % (6/101)
Chi-square test	p = 0.6312	p = 0.0827	p = 0.0872
Difference between with and without GCS treatment groups	–2.0	–12.5	–7.1
95 % CI of the difference shown by the score test	−12.2, 7.8	−26.8, 1.9	−15.7, 1.2

CI confidence interval, GCS graduated compression stockings, VTE venous thromboembolism
^aAll instances of VTE were asymptomatic DVT; no instances of symptomatic or asymptomatic PE or symptomatic DVT were observed

ISSN: 1477-9560