Fig. 2From: Vitamin K antagonist use: evidence of the difficulty of achieving and maintaining target INR range and subsequent consequencesRisks of adverse outcomes for people with INRs <2.0 or >3.0. Adapted from data from an observational study using the Veterans Health Administration dataset [38] showing the relative risk (RR) of adverse thrombotic or embolic events in patients with subtherapeutic INRs versus normal INRs and then major bleeding vents with supertherapeutic INRs versus normal INRs. The diamond represents the actual RR with the line representing the 95Â % confidence interval and the blue dashed line representing a RR of 1.0, where the risk of outcomes would have been the same as those with normal INRsBack to article page