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Table 2 Effects and distribution of tissue damage induced by RVV envenomation reacted with treatment of antiplatelets and anticoagulants

From: Aspirin plus tirofiban inhibit the thrombosis induced by Russell’s viper venom

Treatment Degree of ischemic change
Cyanosis Gangrene Mummification Necrosis
Negative (venom only)a All plantar All plantar All plantar All plantar
Aspirin (As) low All plantar All plantar 3/4 plantar 1/2 plantar
Aspirin high All plantar 1/2 plantar none none
Tirofiban (T)b Half plantar Digits none none
Heparin (H) All plantar 1/2 plantar 1/2 plantar 1/2 plantar
Clopidogrel (C) All plantar 1/2 plantar 1/2 plantar 1/2 plantar
Ag and Cc All plantar 3/4 plantar none none
Ag and Hc Digits Digits none none
Ag and Asb none none none none
  1. aReference to Fig. 1
  2. bReference to Fig. 4
  3. cReference to Fig. 5