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Table 1 Definitions of continuous prophylaxis (see reference [1])

From: Individualized prophylaxis for optimizing hemophilia care: can we apply this to both developed and developing nations?

  No. large joint bleeds* Age to start (year) Clinical arthropathy, osteochondral disease
Primary ≤1 ≤3 absent
Secondary ≥2 any absent
Tertiary ≥2 any present
  1. All refer to continuous prophylaxis intended for 52 weeks per year, and taken for at least 45 weeks of the year under consideration
  2. *large joints =  knees, ankles, elbows, hips, shouders