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Table 1 Definitions of continuous prophylaxis (see reference [1])

From: Individualized prophylaxis for optimizing hemophilia care: can we apply this to both developed and developing nations?

 

No. large joint bleeds*

Age to start (year)

Clinical arthropathy, osteochondral disease

Primary

≤1

≤3

absent

Secondary

≥2

any

absent

Tertiary

≥2

any

present

  1. All refer to continuous prophylaxis intended for 52 weeks per year, and taken for at least 45 weeks of the year under consideration
  2. *large joints =  knees, ankles, elbows, hips, shouders