Fig. 3
From: New horizon in platelet function: with special reference to a recently-found molecule, CLEC-2
CLEC-2-knockout mice have dilated, torturous lymphatic vessels. While blood vessels and lymphatic vessels are distinctly separated in wild-type, they were intermingled with each other with CLEC-2-knockout mice, and the lymphatic vessels are dilated and torturous. PECAM-1 stains blood vessels, and Lyve-1 stains lymphatic endothelial cells. At the sites indicated by arrowheads, blood vessels and lymphatic vessels appear to be connected