Fig. 4
From: New horizon in platelet function: with special reference to a recently-found molecule, CLEC-2
The supernatant of activated platelets inhibited tube formation of lymphatic endothelial cells (LEC) but not that of human umbilical venous endothelial cells (HUVEC). The upper left inlet shows the pattern of LEC tube formation without platelets, and the upper right inlet shows that LEC tube formation is disturbed in the presence of washed platelets which express CLEC-2. On the other hand, tube formation of HUVEC (lower left inlet) is not affected in the presence of platelets (lower right inlet)