From: Proposal for new diagnostic criteria for DIC from the Japanese Society on Thrombosis and Hemostasis
Test | Significance |
---|---|
Plasmin-α2 plasmin inhibitor complex (PIC) | The higher the values, the greater the fibrinolytic activation |
α2 plasmin inhibitor (α2PI) | This is consumed and decreases due to fibrinolytic activation. However, it is also decreased by liver failure alone, and it is elevated in acute inflammatory diseases. |
Protein C (PC) | Low values correlate with a poor prognosis. However, it is also decreased by vitamin K deficiency and/or liver failure alone. |
Plasminogen activator inhibitor-1 (PAI-1) | High values in infectious-type DIC correlate with a poor prognosis. |
HMGB-1 | High values correlate with a poor prognosis. |
e-XDP | Both low and markedly elevated values in infectious-type DIC correlate with a poor prognosis. |