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Table 4 Comparison of HESTIA criteria and exclusion criteria used by Aujesky et al. [2, 3]

From: Pathways for outpatient management of venous thromboembolism in a UK centre

HESTIA criteria: Zondag [3]

Exclusion criteria: Aujesky [2]

Is the patient haemodynamically unstable?

SBP <100 mmHg

Is thrombolysis or embolectomy necessary?

 

>24 h oxygen to maintain sats >90%

Oxygen saturation <90%

Active bleeding or high risk of bleeding

Active bleeding

High risk of bleeding (stroke within the preceding 10 days, GI bleed within the last 14 days or platelet count <75,000/mm3)

PE diagnosed on anticoagulation?

Therapeutic anticoagulation (INR ≥2.0) at diagnosis

Severe pain needing IV pain medication for >24 h

Chest pain needing opiates

Medical or social reason for treatment in hospital (infection, malignancy, no support system)

Barriers to treatment adherence or follow-up

CrCl <30 mL/min

Severe renal failure (CrCl <30 mL/min)

Severe liver impairment

 

Documented history of HIT

HIT

Is the patient pregnant?

 
 

Obesity (weight >150 kg)

  1. CrCl creatinine clearance, GI gastrointestinal, HIT heparin-induced thrombocytopenia, INR international normalised ratio, IV intravenous, PE pulmonary embolism, SBP systolic blood pressure