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Fig. 2 | Thrombosis Journal

Fig. 2

From: Reduced platelet hyper-reactivity and platelet-leukocyte aggregation after periodontal therapy

Fig. 2

Platelet response to stimulation with ADP or oral bacteria (Aggregatibacter actinomycetemcomitans [Aa], Porphyromonas gingivalis [Pg], Tannerella forsythia [Tf], Streptococcus sanguis [Ss] and Streptococcus mutans [Sm]). The mean fluorescence intensity (MFI) of (a) PAC-1 binding, (b) P-selectin (CD62P) and (c) CD63 in response to an agonist was recorded as a measure of reactivity. The data were plotted as fold change in MFI [MFI of individual sample after stimulation/MFI of unstimulated sample in buffer] representing the change in reactivity. Data are presented as means ± standard error of the mean (N = 25). Addition of stimuli induced an increase in platelet surface activation markers when analyzed within each timepoint (P < 0.001 - repeated measures ANOVA). The comparisons between timepoints were analyzed by paired T- test (*P < 0.05, baseline vs. recall)

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