Reduced platelet hyper-reactivity and platelet-leukocyte aggregation after periodontal therapy

Thrombosis Journal

Table 2 Summary of platelet-neutrophil, platelet-monocyte and platelet-lymphocyte complexes formation in response to stimulation

Platelet-neutrophil complexes (Fold change over unstimulated)				Platelet-monocyte complexes (Fold change over unstimulated)				Platelet-lymphocyte complexes (Fold change over unstimulated)
	Baseline	Recall	P-value		Baseline	Recall	P-value		Baseline	Recall	P-value
+ADP	6.9 ± 7.9	8.6 ± 19.3	0.468	+ADP	13.0 ± 19.4	8.4 ± 16.8	0.339	+ADP	4.7 ± 8.1	7.1 ± 10.5	0.072
+Aa	2.1 ± 1.8	6.1 ± 17.5	0.766	+Aa	2.7 ± 2.5	1.9 ± 1.3	0.265	+Aa	7.7 ± 19.2	3.9 ± 8.2	0.483
+Pg	9.4 ± 40.1	2.4 ± 5.6	0.462	+Pg	2.1 ± 3.2	1.2 ± 1.0	0.100	+Pg	1.8 ± 2.1	2.0 ± 3.0	0.535
+Tf	32.9 ± 56.2	14.9 ± 30.5	0.028	+Tf	8.7 ± 8.3	7.7 ± 19.6	0.072	+Tf	11.5 ± 23.2	9.3 ± 12.1	0.431
+Ss	51.3 ± 93.4	15.4 ± 31.9	0.003	+Ss	13.2 ± 20.1	7.0 ± 25.1	0.004	+Ss	4.1 ± 10.6	3.9 ± 5.9	0.529
+Sm	1.4 ± 1.4	2.7 ± 7.8	0.906	+Sm	2.2 ± 2.0	1.2 ± 1.2	0.046	+Sm	1.4 ± 0.8	2.7 ± 3.8	0.087

Values are presented as means ± standard deviations. The platelet-neutrophil complexes, platelet-monocyte complexes, platelet-lymphocyte complexes were calculated as percentages platelet-positive neutrophils, monocytes or lymphocytes from the total number of neutrophils, monocytes or lymphocytes, respectively. The fold change over unstimulated values represent the ratios between the measured values after stimulation with ADP, Aa, Pg, Tf, Ss or Sm and in the absence of stimulation (cells in buffer). P-values were obtained by paired T-test and the significant values are given in bold
ADP (adenosine diphosphate), Aa (Aggregatibacter actinomycetemcomitans), Pg (Porphyromonas gingivalis), Tf (Tannerella forsythia), Ss (Streptococcus sanguis), Sm (Streptococcus mutans)

ISSN: 1477-9560