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Table 3 Univariate analysis and odds ratio of thrombin generation test and the biomarkers of hypercoagulability for the positive IVF outcome

From: Impact of blood hypercoagulability on in vitro fertilization outcomes: a prospective longitudinal observational study

Variables

T0

T1

T2

T3

odds ratio

(95% Conf. Interval)

p

odds ratio

(95% Conf. Interval)

p

odds ratio

[95% Conf. Interval)

p

odds ratio

(95% Conf. Interval)

p

lag-time (min)

1.288

(0.39–4.17)

0.672

0.855

(1.96–3.71)

0.835

1.583

(0.54–4.64)

0.403

2.564

(0.11–54.54)

0.56

ETP (nM.min)

0.999

(0.99–1.00)

0.936

1.002

(1.00–1.00)

0.047*

1.002

(1.00–1.003)

0.016*

1.000

(0.99–1.00)

0.625

Peak (nM)

0.999

(0.6–2.2)

0.974

1.013

(1.00–1.02)

0.006*

1.018

(1.01–1.03)

0.004*

1.001

(0.98–1.02)

0.952

ttPeak (min)

1.148

(0.59–2.23)

0.684

0.529

(0.13–2.16)

0.375

1.034

(0.40–2.66)

0.945

1.944

(0.42–8.93)

0.394

MRI (nM/min)

0.997

(0.98–1.01)

0.792

1.032

(1.01–1.05)

0.003*

1.037

(1.01–1.06)

0.005*

0.993

(0.96–1.02)

0.715

Procoag-PPL (sec)

1.009

(0.88–1.15)

0.895

1.399

(1.07–1.82)

0.013*

1.421

(1.08–1.86)

0.011*

1.112

(0.91–1.33)

0.32

TFa (pM)

0.329

(0.04–2.96)

0.322

0.0022

(0–0.21)

0.009*

4.60e–08

(2.14e–13.00)

0.007*

1.141

(1.03–1.27)

0.009

TMa (%)

0.997

(0.99–1.00)

0.598

0.987

(0.96–1.01)

0.223

0.977

(0.95–1.00)

0.107

0.993

(0.96–1.01)

0.368

FVIII (%)

1.003

(0.97–1.02)

 

1.004

(0.97–1.03)

0.799

1.028

(0.99–1.06)

0.137

1.143

(0.97–1.34)

0.119

VWF (%)

1.052

(1.01–1.08)

0.004*

1.009

(0.98–1.04)

0.578

1.012

(0.07–1.05)

0.581

1.062

(0.97–1.16)

0.166

Fibrinogen (g/L)

1.228

(0.48–3.16)

0.67

0.979

(0.18–5.16)

0.981

2.014

(0.31–13)

0.465

6.346

(0.63–63.38)

0.116

D-Dimers (ÎĽg/ml)

0.997

(0.99–1.00)

0.408

1

(0.99–1.00)

0.951

0.992

(0.98–0.99)

0.016*

1.243

(0.82–1.45)

0.234