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Table 2 Management shows significant differences between areas

From: Reduced cardiac function and risk of venous thromboembolism in Asian countries

Management Western countries China Japan
Volume loading 250–500 ml 500 ml None
Anticoagulation therapy Recommended in PE patients with HF Recommended in PE patients with HF For normotensive PE patients without right heart dysfunction
Thrombolytic therapy Considered for PE patients with HF without contradictions Recommended in PE patients with HF without contradictions For PE patients with persistent shock and hypotension
Anticoagulation drugs NOACs combined parenteral anticoagulation Unfractionated heparin only except in few medical centers Unfractionated heparin only except in few medical centers
Thrombolytic drugs Tenecteplase Monteplase Alteplase, reteplase, urokinase