Skip to main content

Table 2 Coagulation markers in supine and after 3 min head-up tilt (HUT) in 178 patients with unexplained syncope, mean ± SD or n (%)

From: Procoagulatory changes induced by head-up tilt test in patients with syncope: observational study

 

All patients

p-value*

Men

Women

p-value¶

N (%)

178

 

81 (46)

97 (54)

 

FVIII:C supine (kIE/L)

1.06 ± 0.38

0.43

1.07 ± 0.32

1.04 ± 0.41

0.56

FVIII:C HUT (kIE/L)

1.07 ± 0.36

 

1.07 ± 0.35

1.07 ± 0.36

0.98

VWF:Ag supine (kIE/L)

1.22 ± 0.54

<0.001

1.28 ± 0.56

1.17 ± 0.51

0.17

VWF:Ag HUT (kIE/L)

1.28 ± 0.55

 

1.33 ± 0.59

1.24 ± 0.52

0.31

VWF:GP1bA supine (kIE/L)

1.24 ± 0.55

0.20

1.30 ± 0.59

1.19 ± 0.52

0.19

VWF:GP1bA HUT (kIE/L)

1.26 ± 0.56

 

1.31 ± 0.64

1.23 ± 0.49

0.34

Fibrinogen supine (g/L)

2.75 ± 0.60

<0.001

2.67 ± 0.57

2.81 ± 0.62

0.11

Fibrinogen HUT (g/L)

2.84 ± 0.60

 

2.73 ± 0.59

2.93 ± 0.60

0.022

LA1 supine (sec)

31.2 ± 3.7

0.066

31.9 ± 3.50

30.7 ± 3.8

0.027

LA1 HUT (sec)

31.1 ± 4.7

 

32.0 ± 3.92

30.5 ± 5.2

0.030

APC-resistance supine

2.60 ± 0.41

<0.001

2.65 ± 0.39

2.57 ± 0.42

0.17

APC-resistance HUT

2.42 ± 0.43

 

2.49 ± 0.41

2.36 ± 0.44

0.044

APTT/C+ supine (sec)

84.3 ± 19.6

<0.001

85.8 ± 19.8

83.1 ± 19.5

0.36

APTT/C+ HUT (sec)

75.1 ± 18.8

 

77.4 ± 18.7

73.1 ± 18.7

0.13

APTT/C- supine (sec)

32.1 ± 3.8

<0.001

32.1 ± 4.1

32.1 ± 3.6

1.0

APTT/C- HUT (sec)

30.8 ± 3.7

 

30.8 ± 3.8

30.7 ± 3.7

0.83

  1. *supine vs. HUT paired samples t-test; ¶ men vs. women independent samples t-test; FVIII, factor VIII; VWF:Ag, von Willebrand factor antigen; vVWF:GP1bA, von Willebrand factor GP1bA activity; LA1, lupus anticoagulant-screening; APC-resistance, activated protein C resistance; APTT, activated prothrombin time; C+/−, with/without activated protein C