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Table 3 Gender-stratified changes in coagulation markers during head-up tilt among 178 patients with unexplained syncope

From: Procoagulatory changes induced by head-up tilt test in patients with syncope: observational study

  Men p-value* Women p-value*
N (%) 81 (46)   97 (54)  
Δ FVIII:C (kIE/L) 0.00 ± 0.16 0.64 0.02 ± 0.13 0.091
Δ VWF:Ag (kIE/L) 0.04 ± 0.18 0.030 0.07 ± 0.15 <0.001
Δ VWF:GP1bA (kIE/L) 0.01 ± 0.25 0.86 0.03 ± 0.18 0.067
Δ Fibrinogen (g/L) 0.06 ± 0.32 0.12 0.12 ± 0.22 <0.001
Δ LA1 (sec) −0.13 ± 3.23 0.72 −0.56 ± 1.96 0.007
Δ APC-resistance −0.16 ± 0.26 <0.001 −0.21 ± 0.26 <0.001
Δ APTT/C+ (sec) −8.3 ± 13.7 <0.001 −9.9 ± 10.6 <0.001
Δ APTT/C- (sec) −1.2 ± 2.4 <0.001 −1.4 ± 1.7 <0.001
  1. *supine vs. HUT paired samples t-test; FVIII, factor VIII; VWF:Ag, von Willebrand factor antigen; vWF:GP1bA, von Willebrand factor GP1bA activity; LA1, lupus anticoagulant-screening; APC-resistance, activated protein C resistance; APTT, activated prothrombin time; C+/−, with/without activated protein C