Skip to main content

Advertisement

Table 4 Age-stratified changes in coagulation markers during head-up tilt among 178 patients with unexplained syncope

From: Procoagulatory changes induced by head-up tilt test in patients with syncope: observational study

  Age < 65 years p-value* Age ≥ 65 years p-value*
N (%) 119 (67)   59 (33)  
Δ FVIII:C (kIE/L) 0.02 ± 0.15 0.17 −0.01 ± 0.15 0.55
Δ VWF:Ag (kIE/L) 0.04 ± 0.15 0.006 0.10 ± 0.19 <0.001
Δ VWF:GP1bA (kIE/L) 0.02 ± 0.22 0.35 0.02 ± 0.19 0.37
Δ Fibrinogen (g/L) 0.10 ± 0.30 <0.001 0.07 ± 0.20 0.009
Δ LA1 (sec) −0.40 ± 2.88 0.14 −0.31 ± 1.92 0.25
Δ APC-resistance −0.16 ± 0.24 <0.001 −0.24 ± 0.28 <0.001
Δ APTT/C+ (sec) −8.5 ± 12.2 <0.001 −10.6 ± 11.9 <0.001
Δ APTT/C- (sec) −1.3 ± 2.1 <0.001 −1.3 ± 2.0 <0.001
  1. *supine vs. HUT paired samples t-test; FVIII, factor VIII; VWF:Ag, von Willebrand factor antigen; vWF:GP1bA, von Willebrand factor GP1bA activity; LA1, lupus anticoagulant-screening; APC-resistance, activated protein C resistance; APTT, activated prothrombin time; C+/−, with/without activated protein C