Fig. 2
Defective clot retraction and αIIbβ3 activation upon transfusion of DiYF but not WT platelets. a Platelet counts before irradiation (n = 12), after irradiation (control, n = 12) and after platelet transfusions (both n = 8). b Defective platelet retraction function in WT mice with DiYF platelets; Characteristics of clot retraction after 15, 30 and 60 min in transfused WT and DiYF PRP samples. Quantification of significantly increased clot volumes in transfused DiYF platelets compared to WT platelets is shown as a graph in the bottom right panel (mean ± SEM from five independent experiments). c Defective platelet αIIbβ3 activation in WT mice with DiYF platelets (mean ± SEM from three independent experiments)