From: Effect of sinus rhythm restoration on markers of thrombin generation in atrial fibrillation
Variable | No warfarin (n = 13) | Warfarin (n = 28) | p |
---|---|---|---|
Medical history | |||
Age (years) | 59 ± 12 | 68 ± 9 | 0.008 |
Sex (women/men) | 4/9 | 6/22 | 0.698 |
Body mass index (kg/m2) | 25 ± 3 | 25 ± 2 | 0.602 |
Hypertension | 2 (15%) | 12 (43%) | 0.156 |
Coronary heart disease | 1 (8%) | 5 (18%) | 0.645 |
Diabetes | 1 (8%) | 0 | 0.317 |
Chronic obstructive pulmonary disease | 0 | 1 (4%) | 1.0 |
Current cigarette smoking | 3 (23%) | 2 (7%) | 0.307 |
CHA2DS2-VASc score | 1.2 ± 1.3 | 2.1 ± 1.5 | 0.177 |
Medication | |||
Angiotensin receptor blocker/study drug | 6 (46%) | 12 (43%) | 0.843 |
Angiotensin-converting enzyme inhibitor | 0 | 0 | – |
Beta-blockers | 3 (23%) | 11 (39%) | 0.481 |
Calcium channel blockers | 3 (23%) | 8 (29%) | 1.0 |
Diuretics | 0 | 2 (7%) | 1.0 |
Statins | 1 (8%) | 9 (32%) | 0.129 |
Antiplatelet therapy | 2 (15%) | 0 | 0.095 |
Blood pressure and heart rate | |||
Systolic blood pressure (mmHg) | 129 ± 18 | 140 ± 17 | 0.060 |
Diastolic blood pressure (mmHg) | 78 ± 6 | 80 ± 7 | 0.401 |
Ventricular heart rate (beats per minute) | 59 ± 7 | 58 ± 14 | 0.857 |