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Table 3 AF patients in SR with discontinued warfarin treatment at study end versus the reference group

From: Effect of sinus rhythm restoration on markers of thrombin generation in atrial fibrillation

Variable

AF patients (n = 13)

Reference group (n = 49)

p

Medical history

 Age (years)

59 ± 12

62 ± 0

0.298

 Sex (women/men)

4/9

20/29

0.509

 Body mass index (kg/m2)

25 ± 3

26 ± 4

0.253

 Hypertension

2 (15%)

18 (37%)

0.192

 Coronary heart disease

1 (8%)

2 (4%)

0.513

 Diabetes

1 (8%)

4 (8%)

1.0

 Chronic obstructive pulmonary disease

0

1 (2%)

1.0

 Current cigarette smoking

3 (23%)

7 (14%)

0.432

Medication

 Angiotensin receptor blocker/study drug

6 (46%)

13 (27%)

0.192

 Angiotensin-converting enzyme inhibitor

0

1 (2%)

1.0

 Beta-blockers

3 (23%)

4 (8%)

0.153

 Calcium channel blockers

3 (23%)

4 (8%)

0.153

 Diuretics

0

4 (8%)

0.571

 Statins

1 (8%)

11 (22%)

0.431

 Antiplatelet therapy

2 (15%)

5 (10%)

0.630

Blood pressure and heart rate

 Systolic blood pressure (mmHg)

129 ± 18

134 ± 15

0.326

 Diastolic blood pressure (mmHg)

78 ± 6

78 ± 8

0.779

 Ventricular heart rate (beats per minute)

59 ± 7

64 ± 10

0.072

  1. Clinical characteristics of atrial fibrillation patients maintaining sinus rhythm for 6 months without warfarin treatment at study end (n = 13) versus the reference group (n = 49).Values presented as mean ± standard deviation or number (%). Abbreviations: AF Atrial fibrillation; n Number of patients, SR Sinus rhythm