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Fig. 2 | Thrombosis Journal

Fig. 2

From: Four-factor prothrombin complex concentrate improves thrombin generation and prothrombin time in patients with bleeding complications related to rivaroxaban: a single-center pilot trial

Fig. 2

Effect of four-factor PCC on coagulation parameters. ETP (a), Cmax (b), CTEXTEM (c) and QuickPT (d) for all patients from V1 to V10. Normal (healthy persons without anticoagulation) values are indicated (red area). Significant differences from baseline were determined using the Wilcoxon signed-rank test (*p < 0.05, **p < 0.01). Abbreviations: ETP, endogenous thrombin potential; Cmax, thrombin generation, peak thrombin generation; CT, ROTEM®, clotting time; EXTEM, ROTEM®, extrinsic coagulation pathway; QuickPT, Quick value (prothrombin time)

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