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Fig. 3 | Thrombosis Journal

Fig. 3

From: Four-factor prothrombin complex concentrate improves thrombin generation and prothrombin time in patients with bleeding complications related to rivaroxaban: a single-center pilot trial

Fig. 3

Correlations between means of rivaroxaban plasma levels and various coagulation parameters from V1 to V10. Significantly (p < 0.05 for all) correlated parameters were (a) thrombin generation lag time (tlag, linear approximation for tlag = 23.63 + 0.19*x, r = 0.924, p < 0.001); (b) thrombin generation time to peak (tmax, linear approximation for tmax = 63.02 + 0.34*x, r = 0.903, p < 0.001); (c) EXTEM clotting time (CTEXTEM, linear approximation for CT = 65.312 + 0.26*x, r = 0.926, p < 0.001) and (d) thromboelastometry FIBTEM time to maximum velocity (MaxV-tFIBTEM, linear approximation for MaxV-tFIBTEM = 79.132 + 0.205*x, r = 0.887, p < 0.001). Strength of correlation was interpreted by evaluating the correlation coefficient: r 0.9–1.0, very strong correlation; r 0.7–0.89, strong correlation; r 0.5–0.69, moderate correlation; r 0.3–0.49, weak correlation

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Thrombosis Journal

ISSN: 1477-9560

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