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Fig. 2 | Thrombosis Journal

Fig. 2

From: Differential impact of diabetes mellitus on antiplatelet effects of prasugrel and clopidogrel

Fig. 2

Comparison of platelet function after the loading dose (LD) between clopidogrel and prasugrel. a The vasodilator-stimulated phosphoprotein-platelet reactivity index (VASP-PRI) was measured at the indicated time points after the LD. bc Platelets in platelet-rich plasma obtained at the indicated time points were stimulated with 5 μM adenosine diphosphate (ADP) (b) or 20 μM ADP (c). The absolute change in maximal platelet aggregation as assessed by light transmission (baseline – an indicated point) was calculated. Blue lines and red lines represent the prasugrel LD (20 mg) and clopidogrel LD (300 mg), respectively. Values are means ± SEM. Differences in the time course between groups were determined by repeated measures ANOVA

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