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Table 1 Baseline Characteristics of the Study Population

From: Differential impact of diabetes mellitus on antiplatelet effects of prasugrel and clopidogrel

 

Prasugrel

Clopidogrel

 

Variable

(n = 20)

(n = 20)

p-Value

Age, yrs

61.1 ± 11.0

66.1 ± 11.2

0.16

Male, n (%)

17 (85)

13 (65)

0.14

Body mass index, kg/m2

27.4 ± 3.6

26.3 ± 4.3

0.37

Current Smoker, n (%)

7 (35)

4 (20)

0.24

Hypertension, n (%)

13 (65)

17 (85)

0.14

Dyslipidemia, n (%)

15 (75)

11 (55)

0.19

Diabetes, n (%)

8 (40)

7 (35)

0.74

SDB (ODI 3%), n (%)

6 (30)

6 (30)

1.00

Previous MI, n (%)

0 (0)

0 (0)

1.0

Previous AP, n (%)

2 (10)

1 (5)

0.55

Previous PCI, n (%)

2 (10)

1 (5)

0.55

Previous CABG, n (%)

0 (0)

0 (0)

1.0

Previous stroke, n (%)

1 (5)

1 (5)

1.0

PAD, n (%)

0 (0)

0 (0)

1.0

Family History of CAD, n (%)

8 (40)

6 (30)

0.51

LVEF, %

69.9 ± 6.3

69.4 ± 6.2

0.74

eGFR, ml/min/1.73m2

65.8 ± 18.5

68.2 ± 17.2

0.68

Platelet counts, ×103/μL

21.0 ± 5.9

20.0 ± 4.2

0.54

Medications

 Aspirin, n (%)

20 (100)

20 (100)

1.00

 PPI, n (%)

15 (75)

11 (55)

0.19

 OAD, n (%)

8 (40)

4 (20)

0.17

 Insulin therapy, n (%)

0 (0)

1 (5)

0.31

 Statins, n (%)

15 (75)

11 (55)

0.19

 Nitrates, n (%)

6 (30)

3 (15)

0.26

 CCB, n (%)

9 (45)

10 (50)

0.75

 ACEIs/ ARBs, n (%)

11 (55)

11 (55)

1.00

 Beta blockers, n (%)

15 (75)

12 (60)

0.31

  1. Values are mean ± SD or n (%)
  2. ACEIs Angiotensin converting enzyme inhibitors, AP Angina pectoris, ARBs Angiotensin receptor blockers, CABG Coronary artery bypass surgery, CAD Coronary artery disease, CCB Calcium channel blockers, LVEF Left ventricular ejection fraction, MI Myocardial infarction, OAD Oral antidiabetic drug, PCI Percutaneous coronary intervention, PPI Proton pump inhibitor, SDB Sleep-disordered breathing