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Table 5 Sensitivity analysis of outcomes for Na levels taken ≤7 days prior to surgery

From: Could sodium imbalances predispose to postoperative venous thromboembolism? An analysis of the NSQIP database

 

Sodium (mEq/L)

 

< 135

135–145

> 145

 

(n = 71,783)

(n = 646,416)

(n = 7795)

Thromboembolism

1.40 (1.32–1.49)

Reference

1.66 (1.46–1.89)

Mortality

1.36 (1.30–1.41)

Reference

1.40 (1.28–1.53)

Composite morbiditya

2.04 (2.00–2.08)

Reference

3.86 (3.67–4.06)

 Wound

1.27 (1.22–1.32)

Reference

1.28 (1.15–1.43)

 Cardiac

1.24 (1.17–1.31)

Reference

1.42 (1.24–1.62)

 Respiratory

1.67 (1.62–1.72)

Reference

1.96 (1.82–2.11)

 Urinary

2.07 (1.96–2.19)

Reference

4.22 (3.78–4.70)

 CNS

1.36 (1.24–1.49)

Reference

2.34 (1.95–2.81)

 Sepsis

1.65 (1.59–1.70)

Reference

2.20 (2.04–2.38)

Bleeding

1.81 (1.76–1.86)

Reference

2.10 (1.96–2.26)

Return to operation room

1.43 (1.39–1.47)

Reference

1.47 (1.37–1.58)

Readmission (related)b

1.19 (1.12–1.25)

Reference

0.87 (0.73–1.03)

  1. aComposite morbidity considered positive if any of the following are present: wound, cardiac, respiratory, urinary, CNS injury, sepsis or thromboembolism
  2. bSample size: 189,828