Reference (year) | Design | Patients (n) | Inclusion criteria | Injury Severity Score (ISS) | Sampling time (n) | Trauma-induced coagulopathy |
---|---|---|---|---|---|---|
Median (25–75% quartile) | ||||||
[8] (2007) | Prospective cohort (s) | 208 | Full trauma team activation | 17(9–26) | Arrival in the trauma room (1) | Acute traumatic coagulopathy |
[9] (2007) | Prospective cohort (s) | 39 | Traumatic brain injury | 24(14–30) | Arrival in the trauma room (1) | Coagulopathy |
[10] (2008) | Prospective cohort (s) | 208 | Major trauma | 17(9–26) | Immediately on admission to ED (1) | Acute coagulopathy of trauma |
[43] (2009) | Prospective (s) | 42 | Initial blood sample collected within 1Â h | ACT Non-ACT, not shown | Within 1Â h of hospital presentation (1) | Acute coagulopathy of trauma |
[44] (2010) | Prospective (s) | 58 | Not shown | With coagulopathy Without coagulopathy, not shown | Within 1Â h of arrival at hospital | Coagulopathy |
[45] (2011) | Prospective cohort (s) | 334 | Severe polytrauma ISS > 15 | ISS 15–20, 30–50, > 50 | Immediately after ED admission (1) | Trauma-induced coagulopathy |
[46] (2013) | Prospective cohort (s) | 303 | Trauma team activation | Fibrinolytic activity by PAP and ML Normal 6(1–10) Moderate 17(9–28) Severe 25(17–38) | Within 20 min of arrival in the ED (1) | None |
[47] (2014) | Prospective cohort (s) | 163 | Highest-level trauma team activation | Fibrinolytic activity by PAP Normal 9(2–16) Moderate 21(13–25) Severe 28(17–35) | On admission and prior to administration blood product (1) | None |
[48] (2016) | Prospective cohort (s) | 72 | Highest-level trauma team activation | Hyperfibrinolytic by rapid TEG 33(22–41) | The earliest possible time point after injury (1) | Trauma-induced coagulopathy |