Skip to main content

Advertisement

Table 1 JAAM criteria [11] and ISTH overt DIC criteria [22]

From: Recombinant human soluble thrombomodulin improves mortality in patients with sepsis especially for severe coagulopathy: a retrospective study

  JAAM ISTH
Score 1 3 1 2 3
SIRS ≥3 items     
Platelet Count (103/mL) ≥80 and < 120, or > 30% decrease within 24 h < 80 or 50% decrease within 24 h < 100 < 50  
FDP (μg/mL) ≥10 and < 25 ≥25   ≥10 and < 25 (Moderate increase) ≥25 (Strong increase)
PT Ratio ≥1.2     
Prolonged prothrombin time (sec)    3<, < 6 6<  
Fibrinogen level (g/L)    < 1.0   
Diagnosis 4 points or more 5 points or more
  1. These score was assessed using d-dimer if FDP was not measured. The cut off value of d-dimer level were “moderate increase; 5.4–13.2 μg/mL, strong increase; ≥13.2 μg/mL”
  2. JAAM: The revised Japanese Association for Acute Medicine
  3. ISTH: The International Society on Thrombosis and Haemostasis
  4. SIRS: systemic inflammatory response syndrome
  5. Criteria for SIRS (systemic inflammatory response syndrome)
  6. • Temperature: > 38 °C or < 36 °C
  7. • Heart rate: > 90 beats/min
  8. • Respiratory rate: > 20 breath /min or PaCO2 < 32 Torr (< 4.3 kPa)
  9. • White cell blood counts: > 12,000/mm3, < 4,000cells/mm3, or 10% immature (band) forms