Fig. 2From: Pharmacokinetics of rivaroxaban in children using physiologically based and population pharmacokinetic modelling: an EINSTEIN-Jr phase I studySchematic diagram of the integration of modelling and simulation approaches into the pediatric development process of rivaroxaban. Dashed arrows denote work in progress; outcomes of this work will be described in future publications eq., equivalent; PBPK, physiologically based pharmacokinetic; PopPK, population pharmacokinetic.Back to article page