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Fig. 2 | Thrombosis Journal

Fig. 2

From: Pharmacokinetics of rivaroxaban in children using physiologically based and population pharmacokinetic modelling: an EINSTEIN-Jr phase I study

Fig. 2

Schematic diagram of the integration of modelling and simulation approaches into the pediatric development process of rivaroxaban. Dashed arrows denote work in progress; outcomes of this work will be described in future publications eq., equivalent; PBPK, physiologically based pharmacokinetic; PopPK, population pharmacokinetic.

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