k_{a} for tablet and diluted suspension (1 h^{− 1})

0.717

21.3

39.7

63.9

Absorption rate constant

k_{a} for undiluted suspension (1 h^{−1})

0.208

15.4

CL (l h^{−1})

7.26

9.38

26.2

39.2

Clearance for a subject with a body weight of 70 kg

V (l)

50.9

12

N/A

N/A

Volume of distribution in the central compartment for a subject with a body weight of 70 kg

Q (l h^{− 1})

0.928

17.5

N/A

N/A

Intercompartmental clearance

Vp (l)

13.5

51.5

N/A

N/A

Volume of distribution in the peripheral compartment

Exponent for CL scaling

0.323

27.1

–

–

Exponent to scale CL on the individual body weight

Exponent for V scaling

1

Fixed

–

–

Exponent to scale V on the individual body weight

F1

0.648

9.03

N/A

N/A

Relative bioavailability for the rivaroxaban 20 mgequivalent doses in relation to the rivaroxaban 10 mgequivalent doses with F1 = 1 per definition

Residual error (%)

46.6

14.1

–

–

Proportional residual error
