Table 1 Sensory evaluation questionnaire

Please answer the questions about the drugs you are routinely taking.

Have you ever found difficulty taking any of the tablets you are routinely taking?

1. Yes 2. No

Have you ever been unable to identify the drug taken out of the sheet, causing you to stop taking the drug or any other difficulty?

1. Yes 2. No

How many types of drugs are you routinely taking every morning, including the edoxaban film-coated tablet?

[types]

Next, please answer the questions about the edoxaban orally disintegrating (OD) tablet you have just taken.

What is the extent of your satisfaction with the edoxaban OD tablet you have just taken, if your satisfaction with the current medication (edoxaban film-coated tablet) rates 5?

The product name and dose level are printed on this tablet. Was it easy for you to identify that the drug was edoxaban OD tablet 30 mg or 60 mg?

1. Quite easy to identify

2. Easier to identify than the current edoxaban film-coated tablet

3. More difficult to identify than the current edoxaban film-coated tablet

4. Quite difficult to identify

What was your impression about the size of this tablet when you placed it in your mouth?

1. Very large

2. Slightly large

3. Slightly small

4. Very small

What was your impression of the taste and flavor of this drug when it disintegrated in your mouth?

1. Very good

2. Relatively good

3. Relatively bad (i: Tolerable, ii: Not tolerable)

4. Very bad (i: Tolerable, ii: Not tolerable)

→Please give the reason for selecting 1 through 4, if possible:

[Reason:]

Have you found this drug easier to take than the current medication (edoxaban film-coated tablet)?

1. Quite easy to take

2. Slightly easier to take

3. No difference

4. Slightly more difficult to take

5. Quite difficult to take

→Please give the reason for selecting 1 through 5, if possible:

[Reason:]

This drug can be taken both with or without water, and simultaneously with other drugs. The product name and dose level are printed on this tablet.

Do you think that this drug is more convenient to take than the current medication (edoxaban film-coated tablet)?

1. Much more convenient

2. Slightly more convenient

3. No difference

4. Slightly less convenient

5. Much less convenient

→Please give the reason for selecting 1 through 5, if possible:

[Reason:]

Do you think this drug is easier to continue than the current medication (edoxaban film-coated tablet)?

1. Much easier to continue

2. Slightly easier to continue

3. No difference

4. Slightly less easy to continue

5. Much less easy to continue

→Please give the reason for selecting 1 through 5, if possible:

[Reason:]

Do you think that the printed product name and dose level on the tablet make this drug more reliable than the current medication (edoxaban film-coated tablet)?

1. Much more reliable

2. Slightly more reliable

3. No difference

4. Slightly less reliable

5. Much less reliable

This drug will be sold at the same price as the current medication (edoxaban film-coated tablet). Will you want to change to this drug after marketed?

1. Desire to change

2. No desire to change

→Please give the reason for selecting 1 or 2, if possible:

[Reason:]