Table 3 Results of the sensory evaluation questionnaire about edoxaban OD tablets shown by the group
Group 1 (30 mg without water)c N = 32 | Group 3 (30 mg with water)d N = 32 | Group 2 (60 mg without water)e N = 21 | Group 4 (60 mg with water)f N = 21 | ||
|---|---|---|---|---|---|
n (%) | n (%) | n (%) | n (%) | ||
Question 1: Difficulty in ingestion (current) | Yes | 6 (18.8) | 5 (15.6) | 2 (9.5) | 1 (4.8) |
No | 26 (81.3) | 27 (84.4) | 19 (90.5) | 20 (95.2) | |
Question 2: Difficulty in identifying (current) | Yes | 2 (6.3) | 3 (9.4) | 0 (0.0) | 2 (9.5) |
No | 30 (93.8) | 29 (90.6) | 21 (100.0) | 19 (90.5) | |
Question 3: Number of drugs taken simultaneously | 1 typea | 3 (9.4) | 3 (9.4) | 1 (4.8) | 3 (14.3) |
2 types | 6 (18.8) | 2 (6.3) | 4 (19.1) | 1 (4.8) | |
≥3 types | 23 (71.9) | 27 (84.4) | 16 (76.2) | 17 (81.0) | |
Question 4: Degree of satisfaction | Unsatisfactory | 5 (15.6) | 1 (3.1) | 7 (33.3) | 0 (0.0) |
No difference | 15 (46.9) | 21 (65.6) | 6 (28.6) | 14 (66.7) | |
Satisfactory | 12 (37.5) | 10 (31.3) | 8 (38.1) | 7 (33.3) | |
Question 5: Ease in identifying | Quite easy | 7 (21.9) | 7 (21.9) | 6 (30.0) | 8 (38.1) |
Easierb | 8 (25.0) | 11 (34.4) | 7 (35.0) | 3 (14.3) | |
More difficultb | 5 (15.6) | 3 (9.4) | 4 (20.0) | 4 (19.1) | |
Quite difficult | 12 (37.5) | 11 (34.4) | 3 (15.0) | 6 (28.6) | |
Question 6: Size | Very large | 1 (3.6) | 0 (0.0) | 0 (0.0) | 1 (5.0) |
Slightly large | 10 (35.7) | 19 (61.3) | 16 (84.2) | 13 (65.0) | |
Slightly small | 16 (57.1) | 12 (38.7) | 3 (15.8) | 6 (30.0) | |
Very small | 1 (3.6) | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
Question 7: Taste at the time of disintegration | Very good | 5 (16.7) | 5 (20.0) | 1 (5.3) | 5 (27.8) |
Relatively good | 16 (53.3) | 19 (76.0) | 12 (63.2) | 12 (66.7) | |
Relatively bad | 9 (30.0) | 1 (4.0) | 6 (31.6) | 1 (5.6) | |
Very bad | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
Question 8: Ease in ingestion (comparison) | Quite easy to take | 8 (25.0) | 8 (25.8) | 2 (9.5) | 3 (14.3) |
Slightly easier to take | 6 (18.8) | 8 (25.8) | 3 (14.3) | 5 (23.8) | |
No difference | 9 (28.1) | 15 (48.4) | 9 (42.9) | 12 (57.1) | |
Slightly more difficult to take | 8 (25.0) | 0 (0.0) | 7 (33.3) | 1 (4.8) | |
Quite difficult to take | 1 (3.1) | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
Question 9: Convenience | Much more convenient | 7 (21.9) | 3 (9.4) | 2 (9.5) | 6 (28.6) |
Slightly more convenient | 9 (28.1) | 15 (46.9) | 6 (28.6) | 8 (38.1) | |
No difference | 14 (43.8) | 14 (43.8) | 13 (61.9) | 7 (33.3) | |
Slightly less convenient | 2 (6.3) | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
Much less convenient | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
Question 10: Ease of continuation | Much easier to continue | 6 (18.8) | 2 (6.3) | 1 (4.8) | 4 (19.1) |
Slightly easier to continue | 6 (18.8) | 13 (40.6) | 6 (28.6) | 3 (14.3) | |
No difference | 17 (53.1) | 17 (53.1) | 12 (57.1) | 14 (66.7) | |
Slightly less easy to continue | 3 (9.4) | 0 (0.0) | 2 (9.5) | 0 (0.0) | |
Much less easy to continue | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
Question 11: Reliability | Much more reliable | 2 (6.3) | 7 (21.9) | 6 (28.6) | 6 (28.6) |
Slightly more reliable | 11 (34.4) | 9 (28.1) | 5 (23.8) | 5 (23.8) | |
No difference | 19 (59.4) | 16 (50.0) | 10 (47.6) | 10 (47.6) | |
Slightly less reliable | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
Much less reliable | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
Question 12: Desire to change | Desire to change | 12 (44.4) | 19 (63.3) | 6 (30.0) | 10 (55.6) |
No desire to change | 15 (55.6) | 11 (36.7) | 14 (70.0) | 8 (44.4) |