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Table 4 Results of the sensory evaluation questionnaire about edoxaban OD tablets shown by subgroup

From: Sensory evaluation of edoxaban orally disintegrating tablets: an open-label interventional study (secondary publication)

  

Age (< 75 years) N = 54

Age (≥75 years) N = 52

Current difficulty in ingestion (Question 1)

Yes N = 14

No N = 92

n (%)

n (%)

n (%)

n (%)

Question 1: Difficulty in ingestion (current)

Yes

6 (11.1)

8 (15.4)

14 (100.0)

0 (0.0)

No

48 (88.9)

44 (84.6)

0 (0.0)

92 (100.0)

Question 2: Difficulty in identifying (current)

Yes

2 (3.7)

5 (9.6)

2 (14.3)

5 (5.4)

No

52 (96.3)

47 (90.4)

12 (85.7)

87 (94.6)

Question 3: Number of drugs taken simultaneously

1 typea

2 (3.7)

8 (15.4)

1 (7.1)

9 (9.8)

2 types

7 (13.0)

6 (11.5)

2 (14.3)

11 (12.0)

≥3 types

45 (83.3)

38 (73.1)

11 (78.6)

72 (78.3)

Question 4: Degree of satisfaction

Unsatisfactory

7 (13.0)

6 (11.5)

1 (7.1)

12 (13.0)

No difference

27 (50.0)

29 (55.8)

6 (42.9)

50 (54.4)

Satisfactory

20 (37.0)

17 (32.7)

7 (50.0)

30 (32.6)

Question 5: Ease in identifying

Quite easy

17 (31.5)

11 (21.6)

5 (35.7)

23 (25.3)

Easierb

13 (24.1)

16 (31.4)

5 (35.7)

24 (26.4)

More difficultb

11 (20.4)

5 (9.8)

1 (7.1)

15 (16.5)

Quite difficult

13 (24.1)

19 (37.3)

3 (21.4)

29 (31.9)

Question 6: Size

Very large

2 (3.8)

0 (0.0)

0 (0.0)

2 (2.4)

Slightly large

34 (64.2)

24 (53.3)

7 (53.9)

51 (60.0)

Slightly small

17 (32.1)

20 (44.4)

6 (46.2)

31 (36.5)

Very small

0 (0.0)

1 (2.2)

0 (0.0)

1 (1.2)

Question 7: Taste at the time of disintegration

Very good

9 (18.4)

7 (16.3)

2 (14.3)

14 (18.0)

Relatively good

31 (63.3)

28 (65.1)

11 (78.6)

48 (61.5)

Relatively bad

9 (18.4)

8 (18.6)

1 (7.1)

16 (20.5)

Very bad

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

Question 8: Ease of ingestion (comparison)

Quite easy to take

10 (18.9)

11 (21.2)

6 (42.9)

15 (16.5)

Slightly easier to take

14 (26.4)

8 (15.4)

3 (21.4)

19 (20.9)

No difference

22 (41.5)

23 (44.2)

3 (21.4)

42 (46.2)

Slightly more difficult to take

6 (11.3)

10 (19.2)

2 (14.3)

14 (15.4)

Quite difficult to take

1 (1.9)

0 (0.0)

0 (0.0)

1 (1.1)

Question 9: Convenience

Much more convenient

8 (14.8)

10 (19.2)

4 (28.6)

14 (15.2)

Slightly more convenient

22 (40.7)

16 (30.8)

6 (42.9)

32 (34.8)

No difference

23 (42.6)

25 (48.1)

4 (28.6)

44 (47.8)

Slightly less convenient

1 (1.9)

1 (1.9)

0 (0.0)

2 (2.2)

Much less convenient

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

Question 10: Ease of continuation

Much easier to continue

6 (11.1)

7 (13.5)

5 (35.7)

8 (8.7)

Slightly easier to continue

16 (29.6)

12 (23.1)

2 (14.3)

26 (28.3)

No difference

29 (53.7)

31 (59.6)

7 (50.0)

53 (57.6)

Slightly less easy to continue

3 (5.6)

2 (3.9)

0 (0.0)

5 (5.4)

Much less easy to continue

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

Question 11: Reliability

Much more reliable

16 (29.6)

5 (9.6)

5 (35.7)

16 (17.4)

Slightly more reliable

16 (29.6)

14 (26.9)

2 (14.3)

28 (30.4)

No difference

22 (40.7)

33 (63.5)

7 (50.0)

48 (52.2)

Slightly less reliable

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

Much less reliable

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

Question 12: Desire to change

Desire to change

28 (57.1)

19 (41.3)

10 (76.9)

37 (45.1)

No desire to change

21 (42.9)

27 (58.7)

3 (23.1)

45 (54.9)

  1. aEdoxaban film-coated tablet only
  2. bcompared with the current medication
  3. OD orally disintegrating