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Table 4 PAR4 cleaving proteases

From: Protease-activated receptors (PARs): mechanisms of action and potential therapeutic modulators in PAR-driven inflammatory diseases

  Protease Major cleavage site Additional cleavage sites
Mammalian proteases Thrombin R47G48  
Trypsin R47G48  
Cathepsin G R47G48  
Kallikrein-14 unknown  
Non-mammalian proteases PA-BJ R47G48  
Thrombocytin R47G48  
Der-P3 unknown  
Gingipain R R47G48  
LepA unknown  
S.pneumoniae proteases unknown  
Bromelain unknown  
Ficin unknown  
Papain unknown