Fig. 6From: Sepsis and septic shock: endothelial molecular pathogenesis associated with vascular microthrombotic diseaseCombined micro-macrothrombotic syndrome in EA-VMTD showing well demarcated symmetrical peripheral gangrene. This photo demonstrates peripheral digit ischemic syndrome in a young man with severe meningococcemia who developed classical “DIC” (TTP-like syndrome). Following a surgical procedure. Severe symmetrical well-demarcated dry gangrenes developed in the fingers of both hands. He survived, but lost gangrenous parts of fingers. This syndrome can be explained by combined micro-macrothrombotic syndrome per “two-path unifying theory” as noted in the textBack to article page