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Table 1 Univariate analysis of Demographics, Comorbidities and Surgical Factors in relation to presence of DVT after TKR

From: Chemoprophylaxis in addition to mechanical prophylaxis after total knee arthroplasty surgery does not reduce the incidence of venous thromboembolism

Characteristic   Presence of DVT Odds Ratio (95% Confidence Interval) P-Value Adjusted Odds Ratio (95% Confidence Interval) P-value
  Total Yes No     
Demographic Variables
Sex     1.77(0.91–1.86) 0.184   
 Male 725 41 (5.7) 684 (94.3)     
 Female 2073 150 (7.1) 1926 (92.9)     
Age (years)      0.671   
 Median (range)   66.06 (40) 65.78 (58)     
 Minimum and maximum 31 and 90       
Ethnicity     7.81 (7.21–8.456) 0.05 1.095 (0.89–1.349) 0.39
 Chinese 2009 (72.7) 137 (6.8) 1872 (93.2)     
 Malay 360 (11.8) 18 (5.0) 342 (95.09)     
 Indian 394 (14.5) 27 (6.9) 367 (93.1)     
 Others 35 (1.0) 6 (82.9) 29 (17.1)     
BMI     2.003 (1.783–2.412) 0.55 1.003 (0.973–1.035) 0.84
 Median (range)   27.95 (28.63) 27.71 (52.46)     
 Interquartile Range   5.45 5.92     
Comorbidities
Hypertension     1.1.1.1.1 0.70 (0.60–1.09) 0.13 0.859 (0.602–1.224) 0.40
 Y   111 (7.0) 1392 (93.0)     
 N   80 (6.2) 1218 (93.8)     
Ischemic Heart Disease     1.1.1.1.1 1.00 (0.62–1.66) 0.99 1.000 (0.549–1.837) 0.99
 Y   19 (6.7) 263 (93.3)     
 N   172 (6.8) 2347 (93.2)     
Diabetes Mellitus     1.1.1.1.1 1.00 (0.69–1.48) 0.96 1.215 (0.78–1.893) 0.388
 Y   34 (6.8) 468 (93.2)     
 N   157 (5.8) 2539 (94.2)     
Cancer     0.65 (0.33–1.62) 0.42   
 Y   7 (8.9) 71 (91.1)     
 N   184 (8.3) 2036 (91.7)     
Smoking     0.06 (0.29–5.01) 0.81 1.29 (0.261–6.377) 0.755
 Y   2 (5.7) 33 (94.3)     
 N   189 (6.8) 2577 (93.2)     
Consumption of Anti-Platelet Drugs     0.56 (0.47–1.45) 0.45 0.834 (0.400–1.738) 0.628
 Y   14 (8.1) 159 (91.9)     
 N   177 (6.7) 2451 (93.3)     
Consumption of NSAIDs     0.88 (0.72–2.00) 0.54 1.297 (0.697–2.415) 0.412
 Y   17 (5.7) 273 (94.3)     
 N   174 (6.9) 2337 (93.1)     
Previous Lower Limb VTE     9.85 (1.23–10.98) 0.00   
 Y   5 (24.0) 16 (76.0)     
 N   187 (6.7) 2592 (93.3)     
Family History of VTE     1.1.1.1.1 1.41 (0.02–1.66) 0.24 3.777 (0.063–22.518) 0.525
 Y   1 (25.0) 4 (75.0)     
 N   190 (6.8) 2606 (93.2)     
Surgical Factors
Length of Stay   Y N    1.152 (1.110–1.194) 0.000
 Median (range)   9.33 (60) 6.42 (28)     
 Interquartile Range   5 2     
Operation Time (minutes)     2.000 (0.954–3.025) 0.55 1.000 (0.996–1.005) 0.889
 Median (range)   121 (213) 119 (353)     
 Interquartile Range   43 28