Table 2 Baseline characteristics and studied parameters of the four groups along with statistical comparison
Group A N = 76 | Group B N = 445 | Group C N = 132 | Group D N = 165 | p-value* | |
|---|---|---|---|---|---|
Age (mean ± SD) | 33.0 ± 4.3 | 33.5 ± 4.6 | 37.2 ± 5.1 | 32.5 ± 4.4 | <.0001 |
BMI (mean, SD) | 25.0 ± 4.3 | 24.4 ± 3.9 | 24.7 ± 3.8 | 24.4 ± 4.3 | 0.2607 |
No. of foetuses at the observed gestation (N. %) | |||||
1 | 73, 96.1% | 434, 97.5% | 102, 77.3% | 158, 95.8% | <.0001 |
≥ 2 | 3, 4.0% | 11, 2.5% | 30, 22.7% | 7, 4.2% | |
Mean Duration of LMWH (months) | 8.7 ± 1.7 | 8.7 ± 1.3 | 8.7 ± 1.7 | 8.3 ± 1.6 | <.0001 |
ASA Duration (months) (N of patients) | 6.7 ± 2.8 (N = 11) | 6.1 ± 2.4 (N = 79) | 5.5 ± 2.8 (N = 39) | 7.9 ± 2.0 (N = 19) | 0.0068 |
Fixed Prophylactic Dose | 34.2% | 58.9% | 50% | 52.1% | <.0001 |
Weight Adjusted prophylactic dose | 21.1% | 32.4% | 38.6% | 37.0% | |
Therapeutic dose of LMWH | 44.7% | 8.8% | 11.4% | 10.9% | |
Concomitant Use of ASA | 14.5% | 18.2% | 30.3% | 12.1% | 0.0006 |
Caesarian | 80.3% | 79.7% | 91.7% | 65.5% | <.0001 |
Live Birth | 97.4% | 99.1% | 97.0% | 99.4% | 0.1632 |
High risk Thrombophilia (positive cases) | 25% | 10.1% | 9.9% | 10.3% | 0.0018 |
APA status (total successful tests N = 363) (% positive cases within group) | 29.6% | 29.1% | 27.1% | 20.4% | 0.6264 |