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Table 7 Events in the total cohort and per group for each dose

From: Low molecular weight heparins use in pregnancy: a practice survey from Greece and a review of the literature

Group A   Fixed dose prophylactic (n = 26) Higher prophylactic (n = 16) Therapeutic (n = 34) p
VTE (pre or postpartum) 3, 11.54% 0 3, 8.82% 0.3894
Bleeding 0 0 1, 2.94% 0.5348
Adverse pregnancy complications 2, 7.69% 2, 12.50% 8, 23.53% 0.2295
IUGR 1, 3.85% 0 1, 2.94% 0.5193
Preterm Labor 0 2, 12.50% 5, 14.71
Fetal Death 0 0 1, 2.94%
Early pregnancy loss/abortion 1, 3.85% 0 0
Pre-eclampsia/eclampsia 0 0 1, 2.94%
Group B   Fixed dose prophylactic (n = 262) Higher prophylactic (n = 144) Therapeutic (n = 39) p
VTE (pre or postpartum) 1, 0.38% 1, 0.69% 3, 7.69% 0.0002
Bleeding 5, 1.91% 1, 0.69% o 0.4462
Adverse pregnancy complications 18, 6.87% 11, 2.47% 3, 7.69% 0.952
IUGR 2, 0.76% 6, 4.17% 0 0.315
Preterm Labor 12, 4.58% 5, 3.47% 2, 5.13%
Fetal Death 1, 0.38% 0 0
Early pregnancy loss/abortion 2, 0.76% 0 1, 2.56%
Pre-eclampsia/eclampsia 1, 0.38% 0 0
Group C   Fixed dose prophylactic (n = 66) Higher prophylactic (n = 51) Therapeutic (n = 15) p
VTE (pre or postpartum) 0 1, 1.96% 0 0.4492
Bleeding 2, 3.03% 3, 5.88% 0 0.5199
Adverse pregnancy complications 8, 12.12% 10, 19.61% 2, 13.33% 0.5226
IUGR 1, 1.52% 4, 7.84% 0 0.4374
Preterm Labor 5, 7.58% 5, 9.80% 2, 13.33%
Fetal Death 0 1, 1.96% 0
Early pregnancy loss/abortion 2, 3.03% 0 0
Pre-eclampsia/eclampsia 0 0 0
Group D   Fixed dose prophylactic (n = 86) Higher prophylactic (n = 61) Therapeutic (n = 18) p
VTE (pre or postpartum) 1, 1.16% 5, 8.20% 0 0.055
Bleeding 0 1, 1.64% 0 0.4242
Adverse pregnancy complications 5, 5.81% 6, 9.84% 1, 5.56% 0.7414
IUGR 0 1, 1.64% 0
Preterm Labor 5, 5.81% 4, 6.56% 1, 5.56%
Fetal Death 0 0 0
Early pregnancy loss/abortion 0 0 0
Pre-eclampsia/eclampsia 0 1, 1.64% 0
All Groups   Fixed dose prophylactic (n = 440) Higher prophylactic (n = 272) Therapeutic (n = 106) p
VTE (pre or postpartum) 5, 1.14% 7, 2.57% 6, 5.66% 0.0151
Bleeding 7, 1.59% 5, 1.84% 1, 0.94% 0.8226
Adverse pregnancy complications 33, 7.50% 29, 10.66% 14, 13.21% 0.1218
IUGR 4, 0.91% 11, 4.04% 1, 0.94% 0.0592
Preterm Labor 22, 5.00% 16, 5.88% 10, 9.43%
Fetal Death 1, 0.23% 1, 0.37% 1, 0.94%
Early pregnancy loss/abortion 5, 1.14% 0 1, 0.94%
Pre-eclampsia/eclampsia 1, 0.23% 1, 0.37% 1, 0.94%