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Table 3 Mean and median bleeding times (min)

From: Effects of concomitant use of prasugrel with edoxaban on bleeding time, pharmacodynamics, and pharmacokinetics of edoxaban in healthy elderly Japanese male subjects: a clinical pharmacology study

 Group 1
30 mg edoxaban plus
2.5 mg prasugrel
Group 2
30 mg edoxaban plus
3.75 mg prasugrel
n = 12n = 12
Baseline
 Mean (SD)3.2 (0.8)3.5 (1.1)
 Median (IQR)3.0 (2.5–3.8)3.5 (2.5–4.5)
Edoxaban administration
 Mean (SD)3.5 (0.6)4.7 (1.6)
 Median (IQR)3.5 (3.0–4.0)4.5 (3.3–6.0)
Edoxaban plus prasugrel administration
 Mean (SD)5.4 (2.3)7.3 (2.8)
 Median (IQR)5.0 (3.5–7.3)7.5 (5.5–10.0)
  1. SD standard deviation, IQR interquartile range